This model also applies to some hereditary cancers as their key mutations, such as BRCA for breast cancer, generally lead to increased ROS and ultimately to repression of mitochondrial activities and up-regulation of glycolysis, as well as hypoxia; hence the energy gap, glucose-metabolite accumulation, hyaluronic acid production and continuous cell division for survival.
Warburg effect; cancer resistance species; carcinogenesis; hyaluronic acid; hypoxia; reactive oxygen species. National Center for Biotechnology Information , U.http://nativehype.ru/components
Testing association of a pathway with survival using gene expression data.
Didn't get the message? Add to My Bibliography. This electron uptake mechanism provides sufficient but minimum energy to drive the reduction of sulfate and other OSS. These results suggest a widespread mechanism for survival of OSS-respiring bacteria via electron uptake from solid minerals in energy-poor marine sediments.
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Generate a file for use with external citation management software. Abstract Bacterial reduction of oxidized sulfur species OSS is critical for energy production in anaerobic marine subsurfaces.
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Images from this publication. Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability.
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Semin Cancer Biol ; Analysis of somatic mutations in cancer tissues challenges the somatic mutation theory of cancer. Similar Papers Loading similar papers….
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